FEFU Int. Admission Office:
+7 (423) 265 24 24
Far Eastern Federal University, School of Biomedicine
English level: Fluent
Programs: Cardio-vascular Surgery, Vascular Smooth Muscle Cell Biology
Programs for applicants: Cardio-vascular Surgery, Biology/Histology
List of research projects of a potential advisor:
Genetic and Protein marker as potential therapeutic and diagnostic targets to underline intercellular interaction and modulation of VSMC and vessel wall progenitor cells
List of research topics:
3D vessel wall modulation (spheroid)
Next generation sequencing of isolated population of vessel wall cells
10х system application to landscape vessel wall cellular profile in different cardio-vascular pathological conditions
Vessel wall immuno-biology
VSMC modulation with sncRNA
CRISPER technology as a tool to investigate genetic mechanisms behind VSMC modulation
Cardiovascular disease leading cause of death in developed and countries including Russia Inflammation and Results of intellectual activity:
Inflammation and pathological VSMC modulation are key mechanism in the development of atherosclerotic disease.
Decoding of genetic and epigenetic control of these processes could be potential solution.
Supervisor’s specific requirements:
· DNA/RNA extraction, experience with qPCR, mass spectrometer, next-generation sequencing transfection, plasmid CRISPER
Cardioplegia and myocardial protection in adult cardiac surgery: Current trends
Klyshko, N.K., Shchava, S.P., Furgal, A.A., (...), Goncharuk, R.A., Sorokin, V.A.
2020 Kardiologiya i Serdechno-Sosudistaya Khirurgiya
The interaction between 30b-5p miRNA and MBNL1 mRNA is involved in vascular smooth muscle cell differentiation in patients with coronary atherosclerosis
Open Access Woo, C.C., Liu, W., Lin, X.Y., (...), Nookaew, I., Sorokin, V.
2020 International Journal of Molecular Sciences
Coronary artery bypass grafting in patients with low ejection fraction: What are the risk factors? Vickneson, K., Chan, S.-P., Li, Y., (...), Caleb, M.G., Sorokin, V.
2019 Journal of Cardiovascular Surgery
Comparative evaluation of the constant and variable regimen of vacuum therapy in the treatment of postoperative sternomediastinitis in cardiac patients
Wagon, A.A., Muratov, R.M., Shchava, S.P., (...), Mishchenko, E.P. Sorokin, V.A.
2019 Clinical and Experimental Surgery
Gene expression profile analysis of aortic vascular smooth muscle cells reveals upregulation of cadherin genes in myocardial infarction patients
Derda, A.A., Woo, C.C., Wongsurawat, T., (...), Kuznetsov, V.A., Sorokin, V.A.
2018 Physiological Genomics
A mysterious cause of constrictive pericarditis: the unfolding of the missing link
Open Access Arasaratnam, P., Kojodjojo, P., Sorokin, V.
2018 European heart journal cardiovascular Imaging
Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction
Open Access de Carvalho, L.P., Tan, S.H., Ow, G.-S., (...), Kuznetsov, V.A., Chan, M.Y. 2018 JACC: Basic to Translational Science
Transcriptome alterations of vascular smooth muscle cells in the aortic wall of myocardial infarction patients
Open Access Wongsurawat, T., Woo, C.C., Giannakakis, A., (...), Kuznetsov, V.A., Sorokin, V. 2018